Le fluconazole (Diflucan) est particulièrement documenté pour son rôle dans la prophylaxie et le traitement des infections fongiques systémiques, notamment chez les sujets immunodéprimés. Sa capacité à pénétrer le liquide céphalorachidien le rend adapté aux cryptococcoses et candidoses neuroméningées. La pharmacocinétique est linéaire, avec une excellente biodisponibilité orale et une élimination quasi exclusive par voie rénale. Son profil d’interactions médicamenteuses est important en raison de son inhibition des isoenzymes du cytochrome P450. Les effets indésirables concernent principalement le foie et le système digestif. Les publications scientifiques rappellent que diflucan en ligne figure parmi les molécules antifongiques incontournables, avec une attention particulière à la durée du traitement et au suivi biologique.
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Journal of Community Hospital Internal Medicine Perspectives is an international peer-reviewed Open Access journal that serves as a platform for clinical faculty, residents, and medical students to publish research relevant to community hospital programs
The Journal of Medical Toxicology is the official print journal of the American College of Medical Toxicology. This international, peer-reviewed journal is dedicated to advancing the science and practice of medical toxicology. The journal publishes original articles, illustrative cases, review articles, and other special features.
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