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I haven't read the entire book yet, but I've really enjoyed the excerpts on WSJ and Slate.
The central objection of the campaign against the book is that Emily Oster, as an economist, lacks medical training and is unqualified to write a book that touches on healthcare and medical issues. (See, e.g., this: http://www.nofas.org/2013/08/16/emily-oster-ten-key-responses/) The other objections seem to flow from this one.
As an economist, Oster's career is built around conducting and analyzing regression studies to tease out complex relationships among multiple variables. That's what microeconomists do, and that's exactly what she's doing here with the many studies on the pregnancy-related questions the book addresses. As such, she's uniquely qualified to write this book and provides a perspective that your Ob-Gyn can't (unless he or she happens to have world-class, doctoral-level training in economics and statistics and lots of time after work to sort through the methodological appendices of thousands of studies).